Endocrine Abstracts

Acromegaly is a rare disease associated with hypersecretion of growth hormone due to adenoma of somatotroph cells in the pituitary gland, with elevated morbidity and mortality. Acromegaly and thyroid diseases show high co-occurrence. In our study; we aimed to determine the relationship between disease activity at the time of admission and after treatment with the presence of goiter, presence of nodules, and possible accompanying thyroid malignancy in 119 patients with acromega...

Acromegaly is a rare disease with high morbidity and mortality associated with excessive secretion of growth hormone due to adenoma of somatotroph cells in the pituitary gland. In patients with acromegaly, residue may remain after surgical treatment, and disease control is attempted with surgery, medical treatment or radiotherapy for these patients. Pituitary imaging, IGF-1 and GH measurement are used in the follow-ups. Dynamic Contrast Enhancement perfusion MRI provides infor...

Pituitary adenomas arise from adenohypophyseal cells and progress with increased comorbidity and mortality. It is important to examine the diagnosis, prevalence, course and treatment of the subgroups of the disease in our country because pituitary adenomas are seen in the most productive periods of life and have important clinical results. In our study, 667 pituitary adenoma patients who applied to Eskişehir Osmangazi University Medical Faculty Hospital Endocrinology Depa...

Developments of the cancer immunology have increased the frequency of use of targeted therapies and immunomodulatory therapies. Although these treatments are effective on cancer cells, they also have toxicity on the thyroid gland. We aimed to evaluate the tyrosine kinase inhibitors(TKI) and immunotherapies-induced thyroid disorders, their relationship on disease prognosis and baseline serum thyroid stimulating hormone (TSH) levels effect on the development of thyroid dysfuncti...

Introduction: Adrenocortical carcinoma (ACC) is a very rare tumor. The mean age at onset is between 40 and 50 years. Patients with nonfunctioning ACC report symptoms of abdominal discomfort or back pain due to the large tumor size. Surgery for ACC should be performed by an expert surgeon.Case: A 29-year-old patient with 25 weeks of pregnancy admitted at our clinic with right side pain. 10×11 cm solid mass on right adrenal gland was detected by ultra...

Introduction: Ganglioneuroma is an extremely rarely seen tumour in the adrenal gland, which originates from neural crest cells. Clinically, they generally have a silent course and in laboratory tests, the hormone levels expressed from the adrenal gland are within the normal range.Case: A 46-year old male patient, for whom a mass in the adrenal gland was diagnosed incidentally on abdominal ultrasonography and MRI. The physical examination, laboratory test...

Introduction: Hypoglycemia is a medical emergency that can have many different causes in etiology. Autoimmune hypoglycemia in patients with very high insulin levels should also be considered in the differential diagnosis.Case: A 50-year-old man was admitted to our clinic for investigation and treatment of hypoglycemic episodes. He did not have any evidence for the use of oral antidiabetic medications, insulin, herbal substances. However, in our history, ...

Introduction and purpose: More than 90% of differentiated thyroid cancers are papillary thyroid cancer (PTC). Lymph node metastasis is common in PTC and has been reported to have no effect on prognosis. The risk of cervical metastasis is high in the presence of clinicopathologic factors including extrathyroidal extension, multifocality and lymphovascular invasion. In this study, it was aimed to evaluate the clinicopathological features of lymph node metastasis development....

Objective: Aspergillosis is defined as the infection of the Aspergillus type mold and is commonly seen in hematologic malignancies, hematopoietic stem cell transplantation, aplastic anemia, primary immunodeficiency, and immunocompromised patients. Fungal sinusitis in diabetes mellitus is generally presented as rhinoorbitocerebral involvement of mucormycosis. Herein, a fungal sinusitis caused by Aspergillus case presented with headache is reported.<p class...

Background and aims: Diabetes is an endocrinological disease with high incidence and important complications. Studies indicate that by 2030, diabetes will affect approximately 366 million people around the world. Neopterin is produced by activated monocyte-macrophages with the induction of interferon gamma and it is accepted as a biomarker of immune activation. Elevated neopterin levels in biological fluids can be observed in neurological, cardiovascular and autoimmune disorde...